CLINICAL MASS SPECTROMETRY GROUP
People
A multidisciplinary team connecting clinical biochemistry, mass spectrometry, metabolomics, lipidomics and translational data analysis.
The Clinical Mass Spectrometry Group brings together clinical laboratory specialists, postdoctoral researchers, PhD students and data analysts working at the interface of laboratory medicine, omics technologies and clinical research.
LEADERSHIP
prof. David Friedecký, Ph.D.
Head
Department of Clinical Biochemistry, University Hospital & Palacký University Olomouc
David Friedecký leads the Clinical Mass Spectrometry Group, focusing on the development and clinical translation of LC-MS/MS methods, metabolomics and lipidomics workflows for laboratory medicine. His work connects clinical biochemistry, inherited metabolic disorders, translational omics and biomarker discovery.
ORCID | Google Scholar | PubMed | Scopus | Web of Science
SENIOR RESEARCHERS & LABORATORY SPECIALISTS
Radana Brumarová, Ph.D.
Radana is interested in biochemical pathways, metabolomics, lipidomics and metabolic disorders. She focuses on biochemical interpretation and evaluation for understanding changes in metabolic pathways.
Hana Janečková, Ph.D.
...
Eliška Ivanovová, Ph.D.
Eliška focuses on targeted multicomponent LC-MS analysis for diagnosis of IEM. Her objective is to develop a screening method with application in clinical practice.
PH.D. STUDENTS
MSc. Jakub Rozhon, 4th year
Jakub specialises in targeted lipidomics and LC-MS/MS analysis, with a focus on lipidomic data processing, statistical evaluation or visualisation. His research mainly focuses on the characterisation of lipidome alterations associated with inflammatory and metabolic diseases. His current projects include lipidomic profiling of paediatric patients with inflammatory bowel diseases and longitudinal investigation of lipidome changes in patients undergoing bariatric surgery. He is also interested in extending lipidomic approaches to unconventional matrices, including honeybee haemolymph.
MSc. Martina Kadláčková, 3rd year
Martina specialises in LC-MS/MS method development and targeted lipidomic analysis. Her research includes the diagnosis and investigation of atypical myopathy in horses, particularly hypoglycin A exposure and related metabolic alterations. She is involved in clinical lipidomics projects focused on infection in synovial fluid, cardiovascular diseases, cancer and autoimmune disorders. Her collaborative work also extends to plant biology, where targeted LC-MS/MS analysis of plant sterols supports research into hormone signalling and sterol metabolism.
MSc. Martina Horejšová, 3rd year
Martina specialises in targeted metabolomics and LC–MS/MS method development. Her research includes the development of a method for the simultaneous determination of cytidine deaminase and deoxycytidylate deaminase activities, with the aim of contributing to improved diagnosis and optimisation of treatment in patients with haematological malignancies. She is also involved in metabolomic profiling of cancer cells, drug-treated cells, metabolic alterations associated with neurodegenerative diseases, and changes related to GPR180 silencing and thermogenesis.
ORCID | LinkedIN
MSc. Antonín Bednář, 2nd year
Antonín specialises in the development of semi-automated data processing workflows in Python, with a focus on improving the efficiency, reproducibility and standardisation of metabolomic and lipidomic data analysis. His work includes the development and optimisation of scripts for processing, evaluating and visualising complex analytical datasets. He is also involved in targeted and untargeted analysis of unconventional biological matrices, including honeybee larvae, human vitreous humour and amniotic fluid.
MSc. Richard Masař, 1st year
Richard's work combines targeted lipidomics and metabolomics using LC-MS/MS with experience in untargeted LC-HRMS profiling. His research covers systemic lupus erythematosus, diabetic retinopathy and hypouricaemia, with an additional focus on cardiovascular risk assessment. He also contributes to LC-MS/MS method development for diagnostic markers of inherited metabolic disorders. Within plant biology collaborations, he supports the development of targeted workflows for sterol analysis and the interpretation of sterol metabolic profiles.
ORCID | LinkedIN
MSc. Nikola Urbánková, 1st year
.
ORCID | LinkedIN
MSc. Natálie Maršálková, 1st year
..